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Cholesterol and micelles

Client:
Merck/Schering-Plough Pharmaceuticals

Title:
The Dual Approach to LDL Cholesterol Reduction

Description:

This 6-minute animation discusses how simultaneous inhibition of both intestinal absorption and hepatic synthesis can lower LDL-cholesterol levels in a complementary manner.

This segment focuses on how cholesterol is absorbed in the small intestine and inserts into micelles, which interact with enterocytes on the villi of the intestinal wall.

A key challenge for this portion: The client wanted the viewer to be able to see the cholesterol and micelle characters at numerous levels of detail to help maximize understanding.

Narration performed by the project’s medical expert.

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