Monoclonal antibodies

Monoclonal antibodies

Project: Targeting multiple myeloma with monoclonal antibodies The monoclonal antibody has become instrumental for the treatment of multiple myeloma. In this sequence, monoclonal antibodies have targeted CD38, a protein commonly expressed on the surface of cancerous plasma cells. Above: Monoclonal antibodies target CD38, a protein commonly expressed on the surface of cancerous plasma cells A…

Carcinoid Syndrome

Carcinoid Syndrome

Project: Sandostatin® LAR Depot MOA This sequence is an excerpt from a 5-minute MOA animation that examines the hypersecretion of hormones in carcinoid syndrome and an advanced biodegradable drug delivery system using polymer microsphere technology and slow release of octreotide. Above: assembly of a biodegradable glucose polymer microsphere Our client gave us a few unique challenges: depict…

Multiple Myeloma

Multiple Myeloma

Project: mAb targeting multiple myeloma MOASequence from 5-minute MOA that provides insight and details for a monoclonal antibody (mAb) designed to induce programmed tumor cell death (apoptosis) and immunomodulatory activity.  Above: Monoclonal antibodies designed to induce programmed tumor cell death (apoptosis) and immunomodulatory activity. For this mechanism of action video, our task was to create…

DHP & Microbes

DHP & Microbes

Project: The Synexis BioDefense System Animation created for the Synexis BioDefense System, a cutting-edge device that converts naturally occurring oxygen and humidity in the air to Dry Hydrogen Peroxide (H2O2), otherwise known as DHP®. Above: Dry Hydrogen Peroxide (DHP) molecules attacking a spore. This unique molecule works continuously to attack the mold, bacteria and viruses (including…

CAR T Therapy

CAR T Therapy

Project: A Closer Look at ABECMA® CAR T Cell Therapy A few selected segments from a 6-minute animation created for a first-in-class B-cell maturation antigen (BCMA)-directed personalized immunotherapy called chimeric antigen receptor (CAR) T-cell therapy. Above: T cells targeting protein BCMA In this CAR T therapy, the T cells are engineered to target a protein…

RNAi Therapy

RNAi Therapy

Project: RNAi Therapeutics: The Incredible Potential of siRNAs This mechanism-of-action animation highlights the therapeutic potential of small interfering RNAs (siRNAs), a powerful approach within RNA interference (RNAi), including an innovative siRNA delivery platform known as Targeted RNAi Molecules. Above: A view of siRNAs Many diseases stem from the overproduction of specific proteins or the presence…