A few frames from animation that depicts the progression of diabetic nephropathy, a driver of chronic kidney disease in people with diabetes. 

Here in the glomerulus, the images show progressive damage to the tubules, damage to podocytes (including loss of them), and scarring as a result of mesangial cells excreting extracellular matrix. 

The last image depicts contracted, granular kidneys from long-term hypertension.

Animation was created for client’s episode on chronic kidney disease and the relationship between type 2 diabetes and cardiovascular risk in patients with advanced CKD.

View here >>

Tagged: anatomy art, biomedical communications, biotech, bowman’s capsule, chronic kidney disease, CKD, diatbetic nephropathy, digital health, extracellular matrix, glomerular disease, glomerular hyperfiltration, hybrid medical, medical animation, medical art, medical marketing, medical visualization, mesangial cells, Minneapolis Minnesota, nephrology, podocytes, scientific animation

Sequence from 5-minute MOA that provides insight and details for a monoclonal antibody (mAb) designed to induce programmed tumor cell death (apoptosis) and immunomodulatory activity.

For this mechanism of action video, our task was to create a science story that would depict several key features: how the mAb finds and binds to myeloma cells and exposes them for elimination, how it boosts cells of the immune system, and how this targeted immunotherapy can kill myeloma cells directly.

View animation >>

Tagged: antibody, biomedical communications, biotech, blood cancer, cancer, cancer immunotherapy, cancer treatment, CD38, hybrid medical, immunotherapy, leukemia, lymphoma, medical animation, medical marketing, monoclonal antibodies, multiple myeloma, myeloid, myeloma awareness, oncology, scientific animation, visual science

Animation created for the Synexis BioDefense System, a cutting-edge device that converts naturally occurring oxygen and humidity in the air to Dry Hydrogen Peroxide (H2O2), otherwise known as DHP™.

This unique molecule works continuously to attack the mold, bacteria and viruses (including SARS-CoV-2) that hide in any type of indoor space.

Our job was to visualize the breakdown and conversion of particles to be converted into DHP, as well as show how DHP molecules are drawn to and destroy various types of viruses, bacteria and mold.

We collaborated closely with our client regarding how the DHP engages with (and destroys) each kind of pathogen, as well as behavior of subatomic particles in the breakdown-and-conversion process inside the catalyst space.

For the complete video, visit synexis.com

View animation >>

Tagged: bacteria, bioart, biodefense, continuous clean, DHP, Dry hydrogen peroxide, health & wellness, hybrid medical, Innovative technology, medical animation, medical marketing, medical visualisation, microbes, microbiology, mold, naturally safe, science, science art, science visuals, scientific animation, Synexis, virology, viruses, visual effects

The monoclonal antibody has become instrumental for the treatment of multiple myeloma.

In this sequence, monoclonal antibodies are seen targeting CD38, a protein commonly expressed on the surface of cancerous plasma cells.

Activation of the complement system triggers the formation of pores in the cellular membrane, leading to cell death.

A goal for this sequence was to explore a visual approach that resembled a deep sea look & feel, including planktonic soft-bodied organisms and other invertebrate animals that live near the ocean floor.

View animation >>

Tagged: antibodies, antibody, antigen, biology class, blood cancer, cancer, CD38, CD38 antibodies, hybrid medical, immune system, mAb, medical animation, medical illustration, medical marketing, medical visualization, monoclonal, multiple myeloma, myeloid, pharmaceutical animation, science, science art, science visuals, scientific animation

Deep in the lungs, we can see the clusters of tiny air sacs — the alveoli — becoming inflamed and filling with pus, making it difficult to breathe.

Pneumonia is an infection of the lungs caused by bacteria, viruses, or even fungi.

View animation >>

Tagged: alveoli, anatomy, biology, hybrid medical, influenza animation, lung anatomy, lung health, medical animation, medical marketing, medical visualisation, Minneapolis Minnesota, pneumonia, pneumonia animation, pneumonia awareness, Pneumonia Day, pneumonia sucks, pneumonia vaccination, pneumonia vaccine, pulmonary, science, science visuals, scientific animation