Here inside this blood vessel, the circulation of red blood cells is obstructed by sickled red blood cells aggregating, sticking together, and leading to an event known as a vaso-occlusive crisis — a central characteristic of sickle cell disease (SCD)

As we zoom out, we are able to see more damage being done in other microvessels.

Sickled red blood cells promote inflammation, obstruct the vasculature, injure the endothelium, and may lead to ischemic damage in vital organs.

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Watch a chimeric antigen receptor (CAR) sprout from the surface of a genetically re-engineered white blood cell.

A chimeric antigen receptor (CAR) sprouts from the surface of a genetically re-engineered white blood cell.

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Tagged: antigens, biology, biomedical communications, cancer, cancer treatment, car-t cell therapy, gene, hybrid medical animation, Minneapolis Minnesota, visual science

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