A few selected sequences we produced for a recent Medscape CME / ABIM MOC / CE symposium titled NASH 101: What You Need to Know Now

The full 2.5- minute animation was developed to be played as a visual aid when the moderator discussed epidemiology and pathogenesis.

We were asked to conceptualize and develop this visual science story. It provides insight into the pathophysiology of NAFLD and NASH, including the role of fatty acids, insulin resistance, and steatosis, as well as mitochondrial dysfunction, excess ROS production, and the stress put on the endoplasmic reticulum inside ballooning hepatocytes. 

In addition, we depicted key attributes of the progression of non-alcoholic steatohepatitis (NASH) including bloated hepatocytes and the fat droplets accumulating inside, displaced cell organelles, lobular inflammation, and the scarring (fibrosis) that occurs as collagen fibers fill the spaces once cell death occurs.

In the last few years, nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH) have become the most common causes of chronic liver disease worldwide. This epidemic is starting to parallel the epidemics of obesity and type 2 diabetes.

View animation >>

Tagged: biology, biomedical communications, cirrhosis, fatty acids, fatty liver disease animation, hepatocytes, hybrid medical, insulin resistance, lipotoxicity, liver animation, medical animation, medical marketing, NAFLD, NASH, NASH liver disease animation, non-alcoholic steatohepatitis, nonalcoholic fatty liver disease, obesity, science visuals, scientific animation, steatohepatitis, steatosis, type 2 diabetes

A close-up fly-through of tumor cells, and the arrival of cytotoxic t cells intent on eradicating them. Activation and proliferation of cytotoxic T cells are critical for immune-mediated tumor destruction.

A key challenge we were given for this sequence: develop a rendering approach that mimics infrared thermal microscopy imaging techniques.

Researchers have been making advancements in understanding the thermal behavior of cells – for example, the ability to read the signatures of tumor cells due to their higher metabolism – in order to be used alongside existing histological analysis methods.

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Tagged: biology, biomedical communications, biotechnology, cancer cells, cytotoxic T cells, fluorescence microscopy, hybrid medical, immune cells, immunology, immunotherapy, infrared, infrared (IR) microscopy, infrared imaging in biology, infrared spectroscopy, IR imaging, IR microscopy, Killer T cell animation, Killer T cells, medical animation, microspectroscopic animation, Minneapolis Minnesota, oncology, pharma, science visuals, scientific animation, T cells, thermal, thermal imaging, thermal microscopy, tumor cells, tumor death

Fat cell enlargement in obesity is related to insulin resistance and type 2 diabetes.

In this sequence, we travel into the visceral fat and see an active environment – teeming with overstressed, damaged fat cells, vasculature, and immune cells.

Stress on these hypertrophic adipocytes results in lipid spillover (fatty acid release) into the circulation, as well as proinflammatory cytokine release and immune cell recruitment.

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Tagged: adipocyte animation, adipocytes, adipose tissue disfunction, diabetes, diabetes 2, diabetes animation, diabetes prevention, fat cell animation, fat cell enlargement, fat cells, hybrid medical, hypertrophic adipocytes, hypertrophic adipose expansion, hypertrophic fat cells, medical animation, medical illustration, medical visualisation, scientific animation, type 2, type 2 diabetes

A few selected segments from a 6-minute animation created for a first-in-class B-cell maturation antigen (BCMA)-directed personalized immunotherapy called chimeric antigen receptor (CAR) T-cell therapy.

In this CAR T therapy, the T cells are engineered to target a protein called BCMA, which is found in abundance on multiple myeloma cells, but is absent from nearly all normal cells.

View animation >>

Tagged: (CAR) T-cell therapy, antigens, biology, biotechnology, cancer, cancer research, cancer treatment, CAR T, CAR T cell animation, CAR T therapy, CAR T-cell animation, car-t cell therapy, chimeric antigen receptor, chimeric antigen receptor animation, gene therapy, hybrid medical, immune health, immunotherapy, medical animation, Medical science, medical visualisation, pharma, scientific animation, T cells, visual science

Sequence from 5-minute MOA that provides insight and details for a monoclonal antibody (mAb) designed to induce programmed tumor cell death (apoptosis) and immunomodulatory activity.

For this mechanism of action video, our task was to create a science story that would depict several key features: how the mAb finds and binds to myeloma cells and exposes them for elimination, how it boosts cells of the immune system, and how this targeted immunotherapy can kill myeloma cells directly.

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Tagged: antibody, biomedical communications, biotech, blood cancer, cancer, cancer immunotherapy, cancer treatment, CD38, hybrid medical, immunotherapy, leukemia, lymphoma, medical animation, medical marketing, monoclonal antibodies, multiple myeloma, myeloid, myeloma awareness, oncology, scientific animation, visual science

Animation created for the Synexis BioDefense System, a cutting-edge device that converts naturally occurring oxygen and humidity in the air to Dry Hydrogen Peroxide (H2O2), otherwise known as DHP™.

This unique molecule works continuously to attack the mold, bacteria and viruses (including SARS-CoV-2) that hide in any type of indoor space.

Our job was to visualize the breakdown and conversion of particles to be converted into DHP, as well as show how DHP molecules are drawn to and destroy various types of viruses, bacteria and mold.

We collaborated closely with our client regarding how the DHP engages with (and destroys) each kind of pathogen, as well as behavior of subatomic particles in the breakdown-and-conversion process inside the catalyst space.

For the complete video, visit synexis.com

View animation >>

Tagged: bacteria, bioart, biodefense, continuous clean, DHP, Dry hydrogen peroxide, health & wellness, hybrid medical, Innovative technology, medical animation, medical marketing, medical visualisation, microbes, microbiology, mold, naturally safe, science, science art, science visuals, scientific animation, Synexis, virology, viruses, visual effects

A few frames from animation that depicts the progression of diabetic nephropathy, a driver of chronic kidney disease in people with diabetes. 

Here in the glomerulus, the images show progressive damage to the tubules, damage to podocytes (including loss of them), and scarring as a result of mesangial cells excreting extracellular matrix. 

The last image depicts contracted, granular kidneys from long-term hypertension.

Animation was created for client’s episode on chronic kidney disease and the relationship between type 2 diabetes and cardiovascular risk in patients with advanced CKD.

View here >>

Tagged: anatomy art, biomedical communications, biotech, bowman’s capsule, chronic kidney disease, CKD, diatbetic nephropathy, digital health, extracellular matrix, glomerular disease, glomerular hyperfiltration, hybrid medical, medical animation, medical art, medical marketing, medical visualization, mesangial cells, Minneapolis Minnesota, nephrology, podocytes, scientific animation

Deep in the lungs, we can see the clusters of tiny air sacs — the alveoli — becoming inflamed and filling with pus, making it difficult to breathe.

Pneumonia is an infection of the lungs caused by bacteria, viruses, or even fungi.

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Tagged: alveoli, anatomy, biology, hybrid medical, influenza animation, lung anatomy, lung health, medical animation, medical marketing, medical visualisation, Minneapolis Minnesota, pneumonia, pneumonia animation, pneumonia awareness, Pneumonia Day, pneumonia sucks, pneumonia vaccination, pneumonia vaccine, pulmonary, science, science visuals, scientific animation

The monoclonal antibody has become instrumental for the treatment of multiple myeloma.

In this sequence, monoclonal antibodies are seen targeting CD38, a protein commonly expressed on the surface of cancerous plasma cells.

Activation of the complement system triggers the formation of pores in the cellular membrane, leading to cell death.

A goal for this sequence was to explore a visual approach that resembled a deep sea look & feel, including planktonic soft-bodied organisms and other invertebrate animals that live near the ocean floor.

View animation >>

Tagged: antibodies, antibody, antigen, biology class, blood cancer, cancer, CD38, CD38 antibodies, hybrid medical, immune system, mAb, medical animation, medical illustration, medical marketing, medical visualization, monoclonal, multiple myeloma, myeloid, pharmaceutical animation, science, science art, science visuals, scientific animation

Segment from a 4-minute animation that explores the pathophysiology of sickle cell disease and the progressive, tissue-damaging effects of chronic hemolysis and anemia.

Our assignment: visually depict several key critical aspects of the SCD story, such as hemoglobin S (HbS) polymerization, red blood cell sickling and tethering, vaso-occlusion, and chronic hemolysis.

Sickled red blood cells promote inflammation, obstruct the vasculature, injure the endothelium, and may lead to ischemic damage in vital organs.

View here >>

Tagged: anemia, biology, biomedical communications, biotech, blood flow, HbS polymer formation, HbS polymerization, hemoglobin S, hemolysis, hybrid medical, intravascular hemolysis, medical animation, medical marketing, pharma, SCD damage, scientific animation, sickle cell, sickle cell anemia, sickle cell awareness, sickle cell disease, sickle cell warrior, vascular, vaso-occlusion, visual science

Patient education animations created for WebMD that explore common medications for type 2 diabetes.

Because each treatment works in a unique way, our task was to bring three medications to life, creating an easy-to-understand mechanism of action story for each science story.

The three medications highlighted on the WebMD website: Metformin, Dipeptidyl Peptidase-4 (DPP-4), and SGLT2 Inhibitors. 

These are selected segments from the larger productions.

View animation >>

Tagged: biology class, diabetes, diabetes 2, diabetes awareness, diabetes community, diabetes life, diabetes prevention, dpp4 inhibitor, hybrid medical, medical animation, medical visualisation, metformin, patient education, science art, science visuals, scientific animation, sglt2 inhibitor, type 2 diabetes, visual effects

Sequence from immersive 1.5-minute 360° animation where we explore the benefits of sleep.

Here within the neural microspace of the brain, we depict the “cleansing system” of the brain: the glymphatic system. 

Just like the rest of your body, the brain accumulates waste. Recent discoveries have shown that cerebral spinal fluid “flushes” debris and metabolic toxins out of the neural microspace during the deep sleep phase. 

We also watch the heart beating (and lungs breathing) inside the chest cavity and discuss the role of sleep in reducing your risk for cardiovascular diseases.

View animation >>

Tagged: 360 animation, benefits of sleep, biology, biomedical communications, biotech, daytime sleepiness, glymphatic system, healing power of sleep, hybrid medical, importance of sleep, insufficient sleep, medical animation, medical marketing, medical visualization, Minneapolis Minnesota, pharma, poor sleep, science visuals, scientific animation, sleep animation, sleep deprivation, sleep disorders, sleeplessness, WebMD animation

Sequence from project that provides insight on the role aberrant DNA methylation has in the abnormalities responsible for cancer cell growth, especially hematological malignancies such as leukemia, lymphoma, and multiple myeloma.

In this sequence, we begin with a view of “normal” DNA methylation, and then change to a view of hypermethylation underway.

Eventually, decitabine – a hypomethylating agent – can be seen moving into place and blocking DNA methyltransferase (DNMT), leading to the degradation of DNMT and eventual hypomethylation.

Targeting DNA methylation with DNA hypomethylating agents (HMAs) acts to reprogram tumor cells to a more normal-like state.

View animation >>

Tagged: aberrant DNA methylation patterns, abnormal methylation, biomedical communications, biotech, cancer, cedazuridine, cytidine deaminase, decitabine, DNA, DNA methylation, DNA methyltransferase inhibitors, DNMT degradation, epigenetic cancer therapy, gene expression, genetic mutations, genetics, hematological malignancies, histones, hybrid medical, hypermethylation, hypomethylating agents, hypomethylation, leukemia, medical animation, medical marketing, nucleosome, oncology, scientific animation

1.5-minute animation created for CME event. 

Our assignment included the development of the science story and creation of key events that would inform and educate viewers on the physiologic functions associated with the endocannabinoid system (ECS), the role of CB1 retrograde signaling, as well as the enzymes involved in the degradation of endocannabinoids.

We had the pleasure and honor of collaborating closely with the speaker of this event; she is also noted for her discovery of the CB1 receptor for cannabinoid agonists.

The target audience included neurologists, primary care physicians, and pediatricians.

View animation >>

Tagged: anandamide, biology, biomedical communications, biotech, cannabinoid animation, cannabis, CB1, CB1 and CB2 receptors, ECS, endocannabinoid system, endocannabinoids, hybrid medical, medical animation, medical marketing, medical visualization, Minneapolis Minnesota, pharma, phytocannabinoids, presynaptic neuron, retrograde signaling, science visuals, scientific animation

Here inside this blood vessel, the circulation of red blood cells is obstructed by sickled red blood cells aggregating, sticking together, and leading to an event known as a vaso-occlusive crisis — a central characteristic of sickle cell disease (SCD)

As we zoom out, we are able to see more damage being done in other microvessels.

Sickled red blood cells promote inflammation, obstruct the vasculature, injure the endothelium, and may lead to ischemic damage in vital organs.

View animation >>

Tagged: anemia, biology, biomedical communications, biotech, blood flow, cells, HbS polymerization, hemoglobin S, hemolysis, hybrid medical, hybrid medical animation, inflammation, ischemic damage, medical animation, pharma, rbc, red blood cells, SCD damage, scientific animation, sickle cell, sickle cell animation, sickle cell awareness, sickle cell disease, sickle cell warrior, vascular, vaso-occlusion, vessel, visual science

Working closely with local book company Lerner Publishing Group, we developed an augmented reality app geared for student learning. This app includes series Space in Action, Gross Bodies and Creepy Crawlies. All now available in stores.

Take a look!

View Demo >>

Download IOS App >>

Download Android App >>

Tagged: antibodies, antibody, antibody animation, antibody drug conjugate, biology, biopharmaceutical drugs, biotechnology, Biotherapeutic, cancer, cancer immunotherapy, cell biology, drug payload, hybrid medical, hybrid medical animation, immunotherapy, medical animation, Medical science, medical visualisation, medicine, monoclonal, monoclonal antibodies, pharma, science, science art, science visuals, scientific animation, therapeutic, visual science

Watch a chimeric antigen receptor (CAR) sprout from the surface of a genetically re-engineered white blood cell.

A chimeric antigen receptor (CAR) sprouts from the surface of a genetically re-engineered white blood cell.

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Tagged: antigens, biology, biomedical communications, cancer, cancer treatment, car-t cell therapy, gene, hybrid medical animation, Minneapolis Minnesota, visual science

Tagged: hybrid medical animation, medical, promotional reel

Large-scale, interactive installation featuring a beating heart and flow simulation of the body’s circulatory system.

The heartbeat and blood flow respond interactively to visitors in the facility: as more people enter the University Center, the heart rate elevates; as they leave, the heartbeat lowers. 

Created in the visual style of an MRI, the 11-foot-tall, 8-foot-wide installation serves as a living welcome to visitors of the Texas Tech Health Sciences Center.

This animation features a few of the sequences we produced for the final piece, including the particle simulations of blood pressure and flow.

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Tagged: art installation, biology, biotech, blood flow, blood pressure, booth design, booth installation, cardiology, conference, exhibit, healthcare, heart anatomy, heart health, hybrid medical, interactive art, interactive health, interactive media, medical animation, new media, pharma, scientific animation, trade show, tradeshow, tradeshow display, vascular, visual science

2.5 minute animation that explores the multiple factors contributing to joint inflammation in rheumatoid arthritis and the role of IL-6, one of the most abundant multifunctional cytokines in the synovial fluid of patients with RA.

IL-6 is a key driver of articular and systemic manifestations and major player in inflammation, immunity, and disease.

View animation >>

Tagged: hybrid medical, immunology, medical animation, pharma animation, Rheumatoid arthritis, rheumatoid arthritis awareness, rheumatology, science education, scientific animation

Augmented reality experience and app developed for the support of our client’s autotransfusion system. Developed as a key global training tool for service technicians, equipment service and support team members.

This in-depth AR experience allows the technician to virtually “place” the AutoLog IQ unit in their own space. Interactive callouts and a user interface help the user locate, examine, and disassemble device components, as well as re-assemble the system parts back into place. Imagine the benefits of this app versus having to locate the correct documentation and finding parts from a schematic.

Because the augmented device environment is a virtual mirror of the actual real-life system, this experience offers technicians the ability to take control of their learning process — on their own time, and at their own location. Videos are also available in the app to support the user experience.

A key for this project was to appropriate the system’s detailed CAD data and convert it into a reasonable format suitable for AR and real-time display.

Our role included all aspects, including close collaboration with the client on overall concept and creation of product’s augmented “story,” production of real-time 3D experience & assets, as well as interface design and deployment of app.

View app in use >>

Tagged: AR, AR training tool, augmented reality, CAD data to AR, immersion, medical device

Video capture of augmented reality app experience that highlights the features and benefits of our client’s innovative transcatheter pulmonary valve therapy device.

Our role included all aspects, including close collaboration with the client on overall concept and creation of product’s augmented “story,” production of real-time 3D experience & assets, as well as interface design and deployment of app.

Working closely with our client, we created an experience that provides the user with first-hand interaction of the device, as well as the ability to explore key features & benefits using a custom user interface design.

Frustrated by the limitations and prohibitive nature of taking prototypes and products on the road, our client is thrilled to now have an effective, high-quality augmented reality experience for use at various shows and events. Having the ability to instantly point out features and benefits using a self-contained AR device is a huge advantage.

Thanks to the immediacy, immersion, and presence that augmented reality provides, the advantages of leveraging the experience for patient education are amazing as well.

While AR and VR appear to be gaining ground in the areas of gaming and social media, healthcare and medical device industries are also beginning to realize their tremendous potential as well.

View app in use >>

Tagged: AR, augmented reality, cardiology, extended reality, immersion, medical device, mixed reality

Excerpt from animation elaborating on the science behind a new sensor technology that measures glucose levels in diabetes. The benefit of the device: no daily finger prick, and testing of glucose levels in a less painful and more efficient manner. Pretty cool.

In this sequence, we zoom down to the surface of the flexible filament to get a closer look at the micro cross-linked polymer matrix environment. As the camera travels through the matrix, glucose molecules can be seen landing, leading to signaling down the length of the cross-linked polymer chain, and reaching the floor of the sensor electrode.

View animation >>

Tagged: blood glucose, blood glucose control, blood glucose levels, diabetes, diabetics, hybrid medical, medical animation, science visuals, scientific animation

AnatomyAR+ augmented reality app for #MERGECube, available on MERGE Miniverse.

We made this video for our augmented reality app; featuring the most thoughtful (yet tough!) critics we could find. We are currently working on some updates and enhancements.

View video >>

Tagged: AR, ARVRinEDU, augmented reality, biology, ed tech, extended reality, kids in AR, MERGE Cube, mixed reality, science education, science visuals, VR, XR

A breach in the skin (from a catheter) has led to an invasion of the bloodstream and profuse growth of the fungus.

Animation created for a closer look at Candida auris — the first identified multidrug-resistant fungus. Injury to cutaneous barriers by catheters allows yeast and fungi to invade deeper structures and enter the bloodstream.

We are honored and thrilled to have this artwork featured on the cover of this year’s Medical Illustration Sourcebook (30th ed).

View animation >>

Tagged: candida auris, candida infection, candidemia, candidiasis, drug resistant, fungal infection, fungus, hybrid medical, hyphae, medical animation, MedIllSB, microbiology, mycology, science art, science visuals

Micro-landscape view of respiratory cells, an accumulating layer of mucus, and Bordetella pertussis bacteria releasing toxins.

A coughing event is occurring here, displacing mucus, the bacteria, and debris.

Also known as whooping cough, pertussis is a highly contagious airborne disease that spreads simply through the coughs and sneezes of an infected person.

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Tagged: biology, bordetella pertussis bacteria, hybrid medical, microbiology, mucus, respiratory cells, science visuals, scientific animation, whooping cough

One of a few sequences we produced for the film “Burden of Genius.”

This documentary explores the life of Dr. Thomas Starzl, a man many call the greatest surgeon of the 20th century and “the father of modern transplantation.”

In 1967, Dr. Starzl stunned the world with the first successful liver transplantation.

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Tagged: biology, documentary, heart, hybrid medical, liver, liver transplant, medical animation, organ transplant, science visuals, transplant, transplant survivor, visual effects

Activated T cells of the immune system targeting and destroying tumor cells. Once lysis occurs, the T cell moves to another cancer cell and repeats the process.

Sequence created for program that explores the impact of immunotherapies for lung cancer.

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Tagged: biology, cancer, hybrid medical, immune system, immunology, immunotherapy, killer cells, medical animation, science visuals, scientific animation, tumor cells

VR experience examining the pathogenesis and inflammatory cycle of psoriatic arthritis.

What does virtual reality provide that a linear video cannot? For this MOA, we immerse the viewer into the inflammatory cycle of psoriatic arthritis and reiterate the story in a non-linear fashion — allowing users the ability to roam around and explore as they wish.

View experience >>

Tagged: ARVRinEDU, biology, ed tech, hybrid medical, immune system, immunology, immunotherapy, Interactive, medical VR, mixed reality, psoriatic arthritis, science education, science visuals, scientific animation, virtual reality, vive, VR

A couple of excerpts from a video production that explores a new advancement in preventing brain injury; specifically, the occurrence of brain injury caused by a concussive blow to the head.

The Q-Collar, developed by Q30 Innovations, assists the body’s own physiology, creating a “bubble-wrap” effect for the brain.

One key visual component of this project involved working closely with the client to execute their concept of slosh mitigation.

View animation >>

Tagged: brain injury, concussion, hybrid medical, medical animation, science art, science visuals, scientific animation

We are excited to release our new demo reel!

A collection of some of our favorite and latest work, featuring segments from medical animation projects we have produced over the past couple of years.

View video >>

Tagged: demo reel, hybrid medical, medical animation, moa, pharma, promotional reel, science education, science visuals, scientific animation

Earlier this summer, we were selected to be developers for the Merge Cube. The video below shows some explorations with augmented reality and the cube.

View video >>

Tagged: AR, ARVRinEDU, augmented reality, biology, ed tech, extended reality, kids in AR, MERGE Cube, mixed reality, science education, science visuals, VR, XR

A few selected segments from an 8-minute animation produced specially for client’s trade show “4D Multisensory” installation.

The 3D interactive ride was featured at the ATS International Conference, the home of pulmonary, critical care and sleep professionals. Attendees experienced a stereoscopic, 3D monorail-style journey through two “branded” cities, learning more about two different patient therapies for COPD.

The XD Theater Experience is a self-contained, motion-simulated, stereoscopic 3D interactive ride often implemented for high-end, media-based trade show attractions.

View online >>

Tagged: 4D Multisensory, ATS International Conference, COPD, critical care, hybrid medical, interactive ride, mechanism of action, medical animation, pulmonary, science education, science visuals, scientific animation, sleep professionals, stereoscopic, stereoscopic 3D, trade show, tradeshow, XD Theater Experience

Some of our favorite work we have produced and explored in 360° VR.

View 360 here >> 

Frame from immersive 360° animation & illustration

View 360 here >>

We were recently in Chicago to present a multi-device virtual and augmented reality showcase. The stations included the Vive, Oculus, Gear VR, Google Cardboard and the Hololens.

Contact us to schedule a demonstration.

Read More >>

Virtual Reality experience we produced for the ASCO 2016 conference.

View the Vr experience >>

Animation of glass lungs and the bronchial pathways inside.

View the animation >>

This 2-minute animation highlights product features for the first “smart” toothbrush, including new 3D
cleaning technology of the dynamic oscillating brush head design.

View the animation >>

At trade shows, you always want to present something that’s cool in order to get the attention of passersby. Whether it is real-time 3D using the Oculus rift, stereoscopid 3D or Leap Motion, Hybrid can develop the technology for your product.

Contact us to discuss custom experience >>

Hybrid is working daily on projects that involve some aspect of leap motion, real-time 3D, virtual reality experience and/or augmentation. As immersive content and the latest emerging technologies become an every-day reality, our goal is to continue leading the way with our dedication to excellence, our artistic approach, and experience.

View the reel >>

We’ve brought together some of our favorite device-related work, featuring segments from projects we have produced over the past couple of years.

View the reel >>

View the animation >>

The client’s challenge: using one fluid, dynamic camera move, “zoom into the eye and through the body in a way that will be intentionally vague overall — yet still have a couple of recognizable stops along the way.”

Rendered specially for a giant 26′ x 5′ screen, the animation was featured in an immersive geodesic dome installation.

View the animation >>

This 4-minute animation showcases the versatile design and broad indications of the Megavac and details how it separates
itself from the competition with the ability to be used for multiple applications.

View the animation >>

Hybrid is on location for a project that will combine live action footage with CGI animation. This live-action shoot will be entirely on green-screen allowing us the ability to digitally reproduce the environment the actors are in. The environment can be anything from a sunny park, the surface of the moon, or in a micro environment.

View photo shoot >>

Illustrations and MOA animation created for medical food that addresses diminished cerebral glucose metabolism (DCGM),
a critical aspect of  Alzheimer’s disease that leaves the brain thirsty for energy.

View Illustrations >>

We’re excited to bring a unique new look for the front end of our website with looping movies created especially for the homepage.

Cycle through the four perfect loops by using the nodes in the upper right corner.

View Homepage >>

A view of a transcytosis underway.

In this depiction, we’ve developed our own hand-drawn cel-shading technique…

View Animation >>

Title sequence – “Ebola Exposed” aired November 22 and created for Discovery Channel UK.

View Animation >>

Hybrid collaborated with VML (and client) to produce The Science of G, a new Gatorade product line.

View interactive experience >>

One of six cancer cell illustrations for large-scale trade show displays.

Also an entry into the Medical Illustrator’s Sourcebook.

View Illustration >>

This 3D interactive scene explains the puzzle of the HIV virus, its life cycle, and
how it reproduces itself in the host.

View life cycle >>

View animation >>

A visual study/exploration of the human heart.

View the animation >>

View full illustration>>

Close-up illustration of a head louse. The strands of hair help understand how large head lice really are.

View the short animation here >>

Part of a large series of illustrations and animations created for a client. We’ve taken a couple of pieces from that project and created this art for the 2011 Medical Illustrator’s Sourcebook page and other promotional purposes.

View Full Double Page Spread >>

An animated reveal of human anatomy.

We wanted to show the complexity and beauty of the human body
by blending between various passes and render styles.

View Animation >>

This is a sequence from a 3-minute animation that examines a unique formulation for building an effective therapy using the latest in nanotechnology, including monomers that organize into a controlled, self-assembling nanotube.

We worked very closely with our clients to deliver a detailed, accurate visualization of key attributes such as nanotube morphology, organization of dimers, and overall formation of the lanreotide nanotube.

View Full Project >>

Collaborating with Vertex Pharmaceuticals, we came up with a way
to combine specific 3D renderings of chemical structures into photographs
depicting “everyday life” scenarios.

View Illustration >>

Animation produced for inclusion into the
Women’s Health area on the Mayo Clinic website.

Part of a series of animations where we have collaborated
with the Mayo Clinic Staff to help achieve a more high-end look to their animations.

View Animation >>

This 2-minute animation examines the unique formulation
of Biotrue™, its ability to match the pH of healthy tears, and the
benefits of keeping tear proteins active.

View Animation >>

Frustrated by the limitations of a traditional product video shoot, our client
called on us to create a functioning photoreal 3D model of the Biocor tissue valve.

This allowed for far more dynamic camera moves and the ability to focus
more clearly on unique product features, such as the flexible stent,
composite construction, and unique shield design.

View Animation >>

With breakthroughs in science animation, Hybrid has helped people envision the
unobservable and the difficult-to-grasp for nearly ten years. With their latest
innovation, it’s you who reveals the beauty in science.

The Hybrid Interactive Heart animation offers viewers a hands-on, completely unique
experience in science visualization and conceptualization.

View Full Project >>