A close-up fly-through of tumor cells, and the arrival of cytotoxic t cells intent on eradicating them. Activation and proliferation of cytotoxic T cells are critical for immune-mediated tumor destruction.

A key challenge we were given for this sequence: develop a rendering approach that mimics infrared thermal microscopy imaging techniques.

Researchers have been making advancements in understanding the thermal behavior of cells – for example, the ability to read the signatures of tumor cells due to their higher metabolism – in order to be used alongside existing histological analysis methods.

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Tagged: biology, biomedical communications, biotechnology, cancer cells, cytotoxic T cells, fluorescence microscopy, hybrid medical, immune cells, immunology, immunotherapy, infrared, infrared (IR) microscopy, infrared imaging in biology, infrared spectroscopy, IR imaging, IR microscopy, Killer T cell animation, Killer T cells, medical animation, microspectroscopic animation, Minneapolis Minnesota, oncology, pharma, science visuals, scientific animation, T cells, thermal, thermal imaging, thermal microscopy, tumor cells, tumor death

Watch a chimeric antigen receptor (CAR) sprout from the surface of a genetically re-engineered white blood cell.

A chimeric antigen receptor (CAR) sprouts from the surface of a genetically re-engineered white blood cell.

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Tagged: antigens, biology, biomedical communications, cancer, cancer treatment, car-t cell therapy, gene, hybrid medical animation, Minneapolis Minnesota, visual science

Deep in the lungs, we can see the clusters of tiny air sacs — the alveoli — becoming inflamed and filling with pus, making it difficult to breathe.

Pneumonia is an infection of the lungs caused by bacteria, viruses, or even fungi.

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Tagged: alveoli, anatomy, biology, hybrid medical, influenza animation, lung anatomy, lung health, medical animation, medical marketing, medical visualisation, Minneapolis Minnesota, pneumonia, pneumonia animation, pneumonia awareness, Pneumonia Day, pneumonia sucks, pneumonia vaccination, pneumonia vaccine, pulmonary, science, science visuals, scientific animation

A few frames from animation that depicts the progression of diabetic nephropathy, a driver of chronic kidney disease in people with diabetes. 

Here in the glomerulus, the images show progressive damage to the tubules, damage to podocytes (including loss of them), and scarring as a result of mesangial cells excreting extracellular matrix. 

The last image depicts contracted, granular kidneys from long-term hypertension.

Animation was created for client’s episode on chronic kidney disease and the relationship between type 2 diabetes and cardiovascular risk in patients with advanced CKD.

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Tagged: anatomy art, biomedical communications, biotech, bowman’s capsule, chronic kidney disease, CKD, diatbetic nephropathy, digital health, extracellular matrix, glomerular disease, glomerular hyperfiltration, hybrid medical, medical animation, medical art, medical marketing, medical visualization, mesangial cells, Minneapolis Minnesota, nephrology, podocytes, scientific animation

Sequence from immersive 1.5-minute 360° animation where we explore the benefits of sleep.

Here within the neural microspace of the brain, we depict the “cleansing system” of the brain: the glymphatic system. 

Just like the rest of your body, the brain accumulates waste. Recent discoveries have shown that cerebral spinal fluid “flushes” debris and metabolic toxins out of the neural microspace during the deep sleep phase. 

We also watch the heart beating (and lungs breathing) inside the chest cavity and discuss the role of sleep in reducing your risk for cardiovascular diseases.

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Tagged: 360 animation, benefits of sleep, biology, biomedical communications, biotech, daytime sleepiness, glymphatic system, healing power of sleep, hybrid medical, importance of sleep, insufficient sleep, medical animation, medical marketing, medical visualization, Minneapolis Minnesota, pharma, poor sleep, science visuals, scientific animation, sleep animation, sleep deprivation, sleep disorders, sleeplessness, WebMD animation

1.5-minute animation created for CME event. 

Our assignment included the development of the science story and creation of key events that would inform and educate viewers on the physiologic functions associated with the endocannabinoid system (ECS), the role of CB1 retrograde signaling, as well as the enzymes involved in the degradation of endocannabinoids.

We had the pleasure and honor of collaborating closely with the speaker of this event; she is also noted for her discovery of the CB1 receptor for cannabinoid agonists.

The target audience included neurologists, primary care physicians, and pediatricians.

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Tagged: anandamide, biology, biomedical communications, biotech, cannabinoid animation, cannabis, CB1, CB1 and CB2 receptors, ECS, endocannabinoid system, endocannabinoids, hybrid medical, medical animation, medical marketing, medical visualization, Minneapolis Minnesota, pharma, phytocannabinoids, presynaptic neuron, retrograde signaling, science visuals, scientific animation