Project: Targeting multiple myeloma with monoclonal antibodies The monoclonal antibody has become instrumental for the treatment of multiple myeloma. In this sequence, monoclonal antibodies have targeted CD38, a protein commonly expressed on the surface of cancerous plasma cells. Above: Monoclonal antibodies target CD38, a protein commonly expressed on the surface of cancerous plasma cells A…
Project: Sandostatin® LAR Depot MOA This sequence is an excerpt from a 5-minute MOA animation that examines the hypersecretion of hormones in carcinoid syndrome and an advanced biodegradable drug delivery system using polymer microsphere technology and slow release of octreotide. Above: assembly of a biodegradable glucose polymer microsphere Our client gave us a few unique challenges: depict…
Project: Your Gut’s Secret World: The Gut Microbiome In this animation, we explore the uniquely individual ecosystem that is your gut microbiome and the intricate environment within the human gut, which supports essential functions such as digestion, vitamin synthesis, pathogen defense, immune response, and even mental health. Above: a view of biofilms The relationship between…
Project: mAb targeting multiple myeloma MOASequence from 5-minute MOA that provides insight and details for a monoclonal antibody (mAb) designed to induce programmed tumor cell death (apoptosis) and immunomodulatory activity. Above: Monoclonal antibodies designed to induce programmed tumor cell death (apoptosis) and immunomodulatory activity. For this mechanism of action video, our task was to create…
Project: HbS Polymerization & Sickle Cell Disease (MOD)Segment from 4-minute (MOD) animation that discusses the pathophysiology of sickle cell disease and the silent damage of SCD that can go unrecognized. Above: a view of sickle cells and chronic hemolysis underway. We were challenged to visually depict several key critical aspects of the SCD story, such…
Project: TOTAL30® Monthly Replacement Contact Lenses Selected segments from a 2.5 minute animation that highlights the features and benefits of a new biomimetic technology that combines a biomimetic surface and unique lens chemistry to help resist bacteria and lipid deposits. Above: polymer nanofibers Durable enough to deliver comfort for a full 30 days of wear,…
Project: Influenza and the Heart MOD Sequence from an animation that explores influenza, the body’s immune response to the virus, and how it may cause dangerous levels of inflammation throughout multiple body organ systems. Above: white blood cells approaching a burgeoning plaque in a blood vessel In this excerpt, we depict a plaque rupture and…
Project: The Synexis BioDefense System Animation created for the Synexis BioDefense System, a cutting-edge device that converts naturally occurring oxygen and humidity in the air to Dry Hydrogen Peroxide (H2O2), otherwise known as DHP®. Above: Dry Hydrogen Peroxide (DHP) molecules attacking a spore. This unique molecule works continuously to attack the mold, bacteria and viruses (including…
Project: Burden of Genius One of several sequences we produced for the film Burden of Genius. This documentary explores the life of Dr. Thomas Starzl, a man many call the greatest surgeon of the 20th century and “the father of modern transplantation.” In 1967, Dr. Starzl stunned the world with the first successful liver transplantation….
Project: A Closer Look at ABECMA® CAR T Cell Therapy A few selected segments from a 6-minute animation created for a first-in-class B-cell maturation antigen (BCMA)-directed personalized immunotherapy called chimeric antigen receptor (CAR) T-cell therapy. Above: T cells targeting protein BCMA In this CAR T therapy, the T cells are engineered to target a protein…